Stephen Rothman is emeritus professor of physiology at the University of California, San Francisco. He was an experimental biologist for more than forty years and is presently engaged in a writing project that considers some of biology’s most difficult questions. Best known for his landmark studies on the transport of protein molecules across biological membranes, he has made notable contributions in everything from molecular biology to whole-animal physiology, and has written or edited seven books, and published more than two hundred articles in Nature, Science, and other prestigious scientific journals.